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Lanthanum Carbonate

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Lanthanum Carbonate Basic information

Product Name:
Lanthanum Carbonate
Synonyms:
  • dilanthanum tricarbonate
  • Carbonic acid, lanthanum(3++) salt (3:2)
  • LANTHANUM CARBONATE
  • LANTHANUM (III) CARBONATE
  • lanthanum(3+) tricarbonate
  • Lanthanum Carbonate powder
  • LANTHANUM CARBONATE
  • lanthanuM carbonat
CAS:
587-26-8
MF:
C3La2O9
MW:
457.84
EINECS:
209-599-5
Product Categories:
  • Inorganics
Mol File:
587-26-8.mol
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Lanthanum Carbonate Chemical Properties

Density 
3.48[at 20℃]
Water Solubility 
1.24mg/L at 20℃
InChI
InChI=1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6
InChIKey
NZPIUJUFIFZSPW-UHFFFAOYSA-H
SMILES
[La+3].[La+3].C([O-])(=O)[O-].C([O-])(=O)[O-].C([O-])(=O)[O-]
CAS DataBase Reference
587-26-8
EPA Substance Registry System
Carbonic acid, lanthanum(3+) salt (3:2) (587-26-8)
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Safety Information

Hazardous Substances Data
587-26-8(Hazardous Substances Data)

MSDS

  • Language:English Provider:ALFA
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Lanthanum Carbonate Usage And Synthesis

Uses

Treatment of hyperphosphatae mia in patients with end stage renal disease.

brand name

Fosrenol (Shire).

Flammability and Explosibility

Not classified

Mechanism of action

Lanthanum Carbonate inhibits phosphate absorption from the intestine and lowers the phosphate levels in the blood. Lanthanum Carbonate inhibits phosphate absorption from the intestine and lowers the phosphate levels in the blood.

Side effects

Nausea, Vomiting, Abdominal pain

in vitro

Lanthanum carbonate is an ideal phosphate binder. It prevents the adsorption of dietary phosphate by forming insoluble lanthanum phosphate. It has been reported that lanthanum carbonate binds phosphate optimally at pH 3–5, while retaining binding activity at pH 1–7. In vitro, studies suggest that the efficacy of lanthanum phosphate is comparable to that of aluminium compounds in binding with phosphate. The FDA has approved using lanthanum carbonate as a phosphate binder for renal failure patients.

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