4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt Basic information
- Product Name:
- 4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt
- Synonyms:
-
- 4,4'-Bis(1-anilinonaphthalene-8-sulfonic Acid) DipotassiuM Salt
- 4,4'-Bis(phenylaMino)-[1,1'-binaphthalene]-5,5'-disulfonic Acid PotassiuM Salt
- 8-Anilino-1-naphthalenesulfonic Acid Di
- 4,4'-DIANILINO-1,1'-BINAPHTHYL-5,5'-DISULFONIC ACID DIPOTASSIUM SALT
- 4,4'-DIANILINO-1,1'-BINAPHTHYL-5,5'-DISULFONIC ACID, POTASSIUM SALT
- BIS-(5,5')-8-ANILINO-1-NAPHTHALENE SULFONIC ACID DIPOTASSIUM SALT
- BIS-ANS
- BIS-ANS DIPOTASSIUM SALT
- CAS:
- 65664-81-5
- MF:
- C32H22K2N2O6S2
- MW:
- 672.85
- Product Categories:
-
- Amines
- Fluorescent Labels & Indicators
- Sulfur & Selenium Compounds
- Aromatics
- Miscellaneous
- Mol File:
- 65664-81-5.mol
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt Chemical Properties
- storage temp.
- Store at -20°C, protect from light
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: slightly soluble; PBS (pH 7.2): 5 mg/ml
- form
- A crystalline solid
- color
- light yellow
- Appearance
- light yellow-green crystals
- BRN
- 5714637
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- F
- 3-10
MSDS
- Language:English Provider:SigmaAldrich
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt Usage And Synthesis
Description
Bis-ANS is a high-affinity fluorescent probe for nonpolar cavities in proteins. Its hydrophobic phenyl and naphthyl rings interact noncovalently with proteins and protein degradation products.
As with other anilinonaphthalene sulfonates (ANS), bis-ANS is essentially nonfluorescent in water but becomes noticeably fluorescent in a nonpolar environment. When free, bis-ANS has an excitation maximum at 390 nm and an emission maximum at 523 nm but undergoes a blue shift with an increase in fluorescence intensity when bound to protein.
Bis-ANS is frequently used to monitor the formation of protein aggregates and indicate protein folding and conformational changes. The dye is also used to detect Aβ fibers.
Uses
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid is a bifunctional fluorescent probe for proteins.
Uses
4,4''-Dianilino-1,1''-binaphthyl-5,5''-disulfonic Acid is a bifunctional fluorescent probe for proteins.
Abs/Em Maxima
396 (free), 401 (complex)/508 (free), 488 (complex) nm
Excitation / Emission Maximum
390 nm (free), 484 nm (bound)/523 nm (free), 496 nm (bound)
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium saltSupplier
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4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt(65664-81-5)Related Product Information
- Sodium diphenylamine-4-sulfonate
- N-Nitrosodiphenylamine
- DIPHENYLAMINE SULFATE
- Naphthalene-2-sulfonic acid
- Diphenylamine
- DIPHENYLAMINE-4-SULFONIC ACID BARIUM SALT
- BIS-ANS (4,4'-DIANILINO-1,1'-BINAPHTHYL-5,5'-DISULFONIC ACID, DIPOTASSIUM SALT)
- 4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic acid dipotassium salt