Basic information Safety Supplier Related

(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O&

Basic information Safety Supplier Related

(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O& Basic information

Product Name:
(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O&
Synonyms:
  • (3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[2,3-f]pyridine-5-carbonitrile
  • Cobimetinib Impurity 1
  • (3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O&
  • (+)-2-Cyano-6-phenyloxazolopiperidine, [3-S-(3α,5β,8ab)]-Hexahydro-3-phenyl-5-H-oxazolo[3,2-a]pyridine-5-carbonitrile
  • [5H.oxazolo[3,2-a]piperidine-5-Carbonitrice,hexahydro-3-phenyl-[3alpha,5beta,8alpha,beta]
  • (3S,5R,8aS)-3-Phenylhexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile
  • XL 518 intermediate
  • 5H-Oxazolo[3,2-a]pyridine-5-carbonitrile, hexahydro-3-phenyl-, (3S,5R,8aS)-
CAS:
106565-71-3
MF:
C14H16N2O
MW:
228.29
EINECS:
634-598-5
Mol File:
106565-71-3.mol
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(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O& Chemical Properties

Melting point:
79-83 °C(lit.)
InChIKey
GQHMNZGZXHZLEN-IUZLNWEFSA-N
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
2
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(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O& Usage And Synthesis

Uses

(3S,5R,8aS)-(+)-Hexahydro-3-phenyl-5H-oxazolo[3,2-a]pyridine-5-carbonitrile can be used as a starting material:

  • To prepare spirocyclic aminochroman derivatives as possible 5-HT1A agonists.
  • In the asymmetric synthesis of aza-analogs of podophyllotoxin as potent antitumor agents.

(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O&Supplier

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(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O&(106565-71-3)Related Product Information