(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine Chemical Properties

Boiling point:

357.6±35.0 °C(Predicted)

Density 

1.150±0.06 g/cm3(Predicted)

pka

-6.31±0.40(Predicted)

InChI

InChI=1S/C14H21NO2S/c1-11-6-8-12(9-7-11)18(16,17)15-10-14(15,5)13(2,3)4/h6-9H,10H2,1-5H3/t14-,15/m0/s1

InChIKey

OKKPTYPQFAFGOT-MLCCFXAWSA-N

SMILES

N1(S(C2=CC=C(C)C=C2)(=O)=O)C[C@]1(C(C)(C)C)C

(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine Usage And Synthesis

Description

(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine is a key intermediate in the synthesis of Ibrexafungerb. Ibrexafungerb is an antimicrobial agent used to treat fungal or yeast infections, including vulvovaginal candidiasis.