ChemicalBook > Product Catalog > Organic Chemistry > Carboxylic acids and derivatives > c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate Basic information
- Product Name:
- c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate
- Synonyms:
-
- c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate
- V2 receptor (V2R) agonist
- Velmupressin acetate
- CAS:
- 1647120-04-4
- MF:
- C44H64ClN11O10S2
- MW:
- 1006.63
- Mol File:
- 1647120-04-4.mol
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c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate Chemical Properties
- form
- Solid
- color
- White to off-white
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c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate Usage And Synthesis
Uses
Velmupressin (c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2) acetate is a potent, selective and short-acting peptidic V2 receptor (V2R) agonist with EC50s of 0.07 and 0.02 nM for hV2R and rV2R, respectively[1].
References
[1] Wi?niewski K, et al. Discovery of Potent, Selective, and Short-Acting Peptidic V2 Receptor Agonists. J Med Chem. 2019 May 23;62(10):4991-5005. DOI:10.1021/acs.jmedchem.9b00132
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