4-KETORETINOL Chemical Properties

Melting point:

102-106°C

Boiling point:

465.5±24.0 °C(Predicted)

Density 

1.013±0.06 g/cm3(Predicted)

storage temp. 

Amber Vial, -20°C Freezer

solubility 

Acetonitrile (Slightly), Chloroform (Slightly)

form 

Yellow Semi-Solid

pka

14.09±0.10(Predicted)

color 

Yellow to Brown Gel to Off-White to Yellow

Stability:

Unstable! Light, Temperature and Moisture Sensitive

CAS DataBase Reference

62702-55-0

4-KETORETINOL Usage And Synthesis

Chemical Properties

Yellow Semi-Solid

Uses

A metabolite of Retinol.

Uses

4-KETORETINOL activate gene expression through binding to nuclear receptor proteins. They are useful for treating leukemia, lymphoma, squamous cell carcinoma, deep (cystic) acne, psoriasis, and photodamaged or aging skin.

Definition

ChEBI: All-trans-4-oxoretinol is a retinoid that is all-trans-retinol in which the hydrogens at position 4 have been replaced by an oxo group. It has a role as an antineoplastic agent. It is a retinoid, a cyclic ketone, an enone and a primary allylic alcohol. It is functionally related to an all-trans-retinol.

4-KETORETINOL(62702-55-0)Related Product Information

• 4-KETO ALL-TRANS-RETINOIC ACID-D3
• 4-KETORETINOL
• 2,4,4-TRIMETHYL-2-CYCLOHEXEN-1-ONE
• 9-cis Retinol
• 4-OXO-TRETINOIN
• Vitamin A
• 4-KETO ALL-TRANS-RETINOIC ACID METHYL ESTER