15(S)-HPETE Chemical Properties

Flash point:

14 °C

storage temp. 

−70°C

solubility 

0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

Safety Information

Hazard Codes 

F

Risk Statements 

11

Safety Statements 

7-16

RIDADR 

UN 1170 3/PG 3

WGK Germany 

1

MSDS

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15(S)-HPETE Usage And Synthesis

Uses

15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 or reduced to 15(S)-HETE by peroxidases. 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.

Uses

15(S)-HPETE is a primary metabolite of arachidonic acid shown to inhibit arachidonic acid induced platelet aggregation.

Definition

ChEBI: The (S)-enantiomer of 15-HPETE.

15(S)-HPETE(70981-96-3)Related Product Information

• 15(S)-HPETE LIPID MAPS
• (+/-)15-HETE
• n-butylhydroperoxide
• 15(S)-HPETE [1-14C]
• 15(S)-HETE
• 15(S)-HPETE, [3H]
• 15(S)-HPETE