OSAJIN
OSAJIN Basic information
- Product Name:
- OSAJIN
- Synonyms:
-
- OSAJIN
- 5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
- 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one
- OSAJIN(RG)
- 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-pyrano[2,3-f]chromen-4-one
- 4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one,5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-
- NSC 21565
- CID 95168
- CAS:
- 482-53-1
- MF:
- C25H24O5
- MW:
- 404.46
- Mol File:
- 482-53-1.mol
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OSAJIN Chemical Properties
- Melting point:
- 189° (uncorr), 193° (corr)
- Boiling point:
- 632.3±55.0 °C(Predicted)
- Density
- 1.258±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- pka
- 7.00±0.40(Predicted)
- color
- Yellow
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OSAJIN Usage And Synthesis
Uses
Osajin is an inhibitor of carbonic anhydrase I and II isoenzymes for therapeutic application such as the treatment of glaucoma.
Definition
ChEBI: Osajin is a member of isoflavanones.
in vivo
Osajin and pomiferin attenuates the myocardial dysfunction provoked by ischemia reperfusion. This is confirmed by an increase in both antioxidant enzyme values and total antioxidant activity. The cardioprotection provided by osajin and pomiferin treatment results from the suppression of oxidative stress and this correlates with improved ventricular function[3].
target
P450 (e.g. CYP17) | Bcl-2/Bax | Caspase
OSAJINSupplier
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
BioBioPha Co., Ltd.
- Tel
- 0871-65217109 13211707573;
- y.liu@mail.biobiopha.com
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
Shanghai Yongye Biotechnology Co., Ltd.
- Tel
- 86-021-61559134 15921386130
- 3423497944@qq.com
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OSAJIN(482-53-1)Related Product Information
- Ipriflavone
- 4-ISOPROPOXYBENZALDEHYDE
- 3'-ALLYL-4'-HYDROXYACETOPHENONE
- 3-Methyl-4-anisaldehyde
- 5'-ETHYL-2'-HYDROXYPROPIOPHENONE
- 2,4-DIMETHOXY-3-METHYLBENZALDEHYDE
- 3-(2-METHOXY-5-METHYLPHENYL)-1-PROPENE
- 2-HYDROXY-4,6-DIMETHOXY-3-METHYLACETOPHENONE
- CHEMBRDG-BB 7918292
- 2,2-Dimethyl-6-acetyl-2H-1-benzopyran
- 3-(3,5-DIMETHYL-4-METHOXYPHENYL)-2-METHYL-1-PROPENE
- 3-(3,5-DIMETHYL-4-METHOXYPHENYL)-1-PROPENE
- 6-METHYLCHROMONE HYDRATE
- 3-(4-Methoxy-3-methylphenyl)prop-1-ene
- 1-[4-(1,1-DIMETHYLETHOXY)PHENYL]-ETHANONE
- OSAJIN
- 2,4-DIHYDROXY-1,3,5-TRIMETHYLBENZENE
- 3',5'-DIMETHYL-2'-HYDROXYPROPIOPHENONE