4-METHYL-3-[(1-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO]-4H-1,2,4-TRIAZOLE Chemical Properties

Boiling point:

553.7±60.0 °C(Predicted)

Density 

1.68±0.1 g/cm3(Predicted)

storage temp. 

Store at +4°C

form 

Solid

pka

0.67±0.10(Predicted)

color 

Light yellow to orange

Water Solubility 

<2.4mg/ml in Water

4-METHYL-3-[(1-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO]-4H-1,2,4-TRIAZOLE Usage And Synthesis

Uses

MNITMT is a novel, non-toxic immunosuppressive agent.

Definition

ChEBI: 4-methyl-3-[(3-methyl-5-nitro-4-imidazolyl)thio]-1,2,4-triazole is an aryl sulfide.

Biological Activity

Novel, non-toxic immunosuppressive agent. Inhibits human mixed lymphocyte reaction in vitro (ED 50 = 2.7 μ M) and prolongs skin graft survival in mice. Produces a 98.1% reduction in antibody response following oral administration in rabbits.

4-METHYL-3-[(1-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO]-4H-1,2,4-TRIAZOLE(177653-76-8)Related Product Information

• JJC 323
• Imidazole, 1-methyl-4-nitro-
• 4-METHYL-3-[(1-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO]-4H-1,2,4-TRIAZOLE