2-CYCLOPENTENYL-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE Chemical Properties

Boiling point:

210.0±33.0 °C(Predicted)

Density 

0.96±0.1 g/cm3(Predicted)

refractive index 

1.46

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

liquid

color 

colorless or yellow

InChI

InChI=1S/C11H19BO2/c1-10(2)11(3,4)14-12(13-10)9-7-5-6-8-9/h7H,5-6,8H2,1-4H3

InChIKey

JFTZVYKESKQING-UHFFFAOYSA-N

SMILES

O1C(C)(C)C(C)(C)OB1C1CCCC=1

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37

TSCA 

No

HS Code 

2931900090

2-CYCLOPENTENYL-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE Usage And Synthesis

Synthesis

Example XIV: Synthesis of 2-cyclopent-1-enyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane Under argon protection, 4.31 g of 1-chloro-1-cyclopentene and 12.5 g of bis(pinacolato)diboron were dissolved in 160 mL of 1,4-dioxane, 8 g of potassium acetate was added, and argon purged for 5 min. Subsequently, 370 mg of tris(dibenzylideneacetylidene)dipalladium(0) ([Pd2(dba)3]) and 780 mg of 2-cyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl were added, and the reaction mixture was heated to 80 °C for 3 hours. After completion of the reaction, it was cooled to room temperature, diluted with diethyl ether, the organic phase was washed with water and brine sequentially, and the organic phase was dried with anhydrous magnesium sulfate. The solvent was removed by evaporation under reduced pressure and the residue was ground with petroleum ether. The precipitate was collected by filtration and the mother liquor was evaporated under reduced pressure to obtain the product. Yield: 13.1 g (99% yield). Mass spectrum (EI): m/z = 194 [M]+.

References

[1] Patent: WO2011/101424, 2011, A1. Location in patent: Page/Page column 230-231
[2] Patent: US2012/46304, 2012, A1. Location in patent: Page/Page column 123
[3] Patent: WO2012/110599, 2012, A1. Location in patent: Page/Page column 230-231
[4] Patent: US2013/53404, 2013, A1. Location in patent: Paragraph 1781; 1782; 1783
[5] Journal of Organic Chemistry, 2012, vol. 77, # 7, p. 3543 - 3548

2-CYCLOPENTENYL-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE(287944-10-9)Related Product Information

• 2-CYCLOPENTENYL-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
• Isopropenylboronic acid pinacol ester
• BUTYLDIISOPROPOXYBORANE
• CYCLOPENTEN-1-YLBORONIC ACID
• 2-BUTYL-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE