4-(Methylamino)phenol Chemical Properties

Melting point:

87 °C

Boiling point:

262.7±23.0 °C(Predicted)

Density 

1.147±0.06 g/cm3(Predicted)

pka

11.31±0.26(Predicted)

CAS DataBase Reference

150-75-4

EPA Substance Registry System

4-(Methylamino)phenol (150-75-4)

Safety Information

RIDADR 

3077

HazardClass 

9

PackingGroup 

III

Hazardous Substances Data

150-75-4 (Hazardous Substances Data)

4-(Methylamino)phenol Usage And Synthesis

Description

4-(Methylamino)phenol is an important organic reagent, with a wide range of pathways, can be used as a reaction reagent for oxidative coupling reaction, analytical detection reagent, photographic developer, corrosion inhibitor for steel in chlorate solution, hair dye developer and so on.

Uses

4-Hydroxy-N-methylaniline is a useful synthetic intermediate. It is used to synthesize arylidene amino azolones with anticancer activity. It is also used to prepare N-(4-hydroxyphenyl)retinamide analogs with antitumor and apoptosis-inducing activities.

Definition

ChEBI: 4-methylaminophenol is the phenol that is the N-methyl derivative of 4-aminophenol. It has a role as an allergen. It is functionally related to a 4-aminophenol.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 43, p. 766, 1995 DOI: 10.1248/cpb.43.766

Contact allergens

Metol is contained in black and white film developers and caused contact dermatitis in photographers.

4-(Methylamino)phenol(150-75-4 )Related Product Information

• o-Cresol
• m-Cresol
• Phenolphthalein
• p-methylamino-pheno sulfate