S-propionylcoenzyme A Chemical Properties

storage temp. 

-20°C

form 

powder

Major Application

lipidomics

InChIKey

QAQREVBBADEHPA-UHFFFAOYSA-N

SMILES

O[C@@](C(NCCC(NCCSC(CC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[Na+].[Na+].[Na+]

Safety Information

WGK Germany 

WGK 3

Storage Class

11 - Combustible Solids

S-propionylcoenzyme A Usage And Synthesis

Uses

lipidomics

Definition

ChEBI: An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of propionic acid.

Biological Activity

03:0 Coenzyme A acts as a substrate for methyl citrate synthase (PrpC), an important enzyme involved in tricarboxylic acid (TCA) cycle. It is a metabolic intermediate in the 1,2-propanediol and propionate degradation pathway of Salmonella enterica serovar Typhimurium LT2. Accumulation of propanoyl coenzyme A due to the deficiency of propionyl-coenzyme A (CoA) carboxylase causes propionic acidemia (PA).

IC 50

Human Endogenous Metabolite