aliconazole
aliconazole Basic information
- Product Name:
- aliconazole
- Synonyms:
-
- aliconazole
- 1-[(Z)-2-(4-Chlorophenyl)-3-(2,4-dichlorophenyl)-2-propenyl]-1H-imidazole
- 1-[(Z)-2,4-Dichloro-β-(4-chlorophenyl)cinnamyl]-1H-imidazole
- 1H-Imidazole, 1-[(2Z)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)-2-propen-1-yl]-
- CAS:
- 63824-12-4
- MF:
- C18H13Cl3N2
- MW:
- 363.67
- EINECS:
- 2644983
- Mol File:
- 63824-12-4.mol
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aliconazole Chemical Properties
- Boiling point:
- 545.0±50.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 6.76±0.12(Predicted)
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aliconazole Usage And Synthesis
Uses
Aliconazole is an antifungal imidazole derivative.
in vivo
Aliconazole was previously in phase III clinical trials for the determination of efficacy in the topical treatment of cutaneous fungal infections. The proposed use includes superficial fungal infections, including dermatomycoses, tinea versicolor, and cutaneous and vaginal candidiasis[1].
References
[1] Fromtling RA, et al. Overview of medically important antifungal azole derivatives. Clin Microbiol Rev. 1988 Apr;1(2):187-217. DOI:10.1128/CMR.1.2.187
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