3'-Azido-3'-deoxythymidine-5'-triphosphate
3'-Azido-3'-deoxythymidine-5'-triphosphate Basic information
- Product Name:
- 3'-Azido-3'-deoxythymidine-5'-triphosphate
- Synonyms:
-
- Zidovudinetriphosphate
- zidovudine 5'-triphosphate
- 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
- 3′-Azido-ddTTP 100mM Sodium Solution
- CAS:
- 92586-35-1
- MF:
- C10H16N5O13P3·xLi
- MW:
- 0
- Mol File:
- 92586-35-1.mol
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3'-Azido-3'-deoxythymidine-5'-triphosphate Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Sticky Solid
- color
- Off-White
- Stability:
- Hygroscopic
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3'-Azido-3'-deoxythymidine-5'-triphosphate Usage And Synthesis
Uses
3'-Azido-3'-deoxythymidine 5’-Triphosphate Tetraammonium Salt, is used for the preparation of drug against human retroviruses.
Biological Activity
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is an active triphosphate metabolite of Zidovudine (AZT). It has antiretroviral activity and inhibits HIV replication.
in vitro
AZT triphosphate causes mitochondrial dysfunction, increases the production of cytotoxic reactive oxygen species (ROS), and impairs the balance of the mitochondrial quality control system in H9c2 cell model established from rat embryonic myoblasts.
target
HIV
HBV
DNA polymerase
Reactive oxygen species (ROS)
3'-Azido-3'-deoxythymidine-5'-triphosphateSupplier
Beijing Jin Ming Biotechnology Co., Ltd.
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- 010-60605840 18892239720
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Beijing Minruida Technology Co., Ltd.
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- 010-82387566 18001021521;
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NewCan Biotech Limited
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- +86-0571-86912261 +8613735419629
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SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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- +86-021-61551413 +8618813727289
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Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840
- psaitong@jm-bio.com
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3'-Azido-3'-deoxythymidine-5'-triphosphate(92586-35-1)Related Product Information
- Zidovudine
- 3'-AZIDO 3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE, TETRATRIETHYLAMMONIUM SALT
- 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, [2-13C-1,3-15N]-
- 3'-AZIDO 3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE, TETRATRIETHYLAMMONIUM SALT, [METHYL-3H]-
- 3'-Azido-3'-deoxythymidine-5'-triphosphate
- 3'-AZIDO-3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE TRI(TRIETHYLAMMONIUM) SALT