Irumamycin
Irumamycin Basic information
- Product Name:
- Irumamycin
- Synonyms:
-
- Irumamycin
- 23-Deoxy-23,24-epoxy-17-hydroxyventuricidin B 3'-carbamate
- 4,21-Dioxabicyclo[15.3.1]heneicosa-9,15,18-trien-3-one, 11-[[3-O-(aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1,7-dihydroxy-6,8,16,18-tetramethyl-5-[(1R,3R)-1-methyl-3-[3-methyl-3-(1-oxopropyl)-2-oxiranyl]butyl]-, (1R,5R,6R,8S,9E,11R,15E,17R)-
- CAS:
- 81604-73-1
- MF:
- C41H65NO12
- MW:
- 763.95
- Mol File:
- 81604-73-1.mol
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Irumamycin Chemical Properties
- Boiling point:
- 886.1±65.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- pka
- 11.82±0.70(Predicted)
- CAS DataBase Reference
- 81604-73-1
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Irumamycin Usage And Synthesis
Uses
Irumamycin is a natural 20-membered macrolide antibiotic. Irumamycin is active in vitro against some phytopathogenic fungi[1]. Irumamycin also shows potent antitrypanosomal activity[2].
IC 50
Macrolide
References
[1] S Omura, et al. Irumamycin, an antifungal 20-membered macrolide produced by a Streptomyces. Taxonomy, fermentation and biological properties. J Antibiot (Tokyo). 1984 Dec;37(12):1572-8. DOI:10.7164/antibiotics.37.1572
[2] Kazuhiko Otoguro, et al. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J Antibiot (Tokyo). 2008 Jun;61(6):372-8. DOI:10.1038/ja.2008.52