Lutrelin
Lutrelin Basic information
- Product Name:
- Lutrelin
- Synonyms:
-
- Lutrelin
- lutrelin acetate
- 5-Oxo-L-Pro-L-His-L-Trp-L-Ser-L-Tyr-D-Trp-N-methyl-L-Leu-L-Arg-L-Pro-ethyl-NH2
- WY-40972
- 1-9-Luteinizing hormone-releasing factor (swine), 6-D-tryptophan-7-(N-methyl-L-leucine)-9-(N-ethyl-L-prolinamide)-
- CAS:
- 66866-63-5
- MF:
- C65H85N17O12
- MW:
- 1296.48
- Mol File:
- 66866-63-5.mol
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Lutrelin Chemical Properties
- Density
- 1.46±0.1 g/cm3(Predicted)
- pka
- 9.82±0.15(Predicted)
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Lutrelin Usage And Synthesis
Uses
Lutrelin (Wy 40972) is a luteinizing hormone releasing hormone (LHRH) agonist. Lutrelin inhibits the growth of the endometrial expiant in rats[1][2].
References
[1] Habenicht UF, et al. Short-term effects of an LHRH-agonist alone or in combination with testosterone propionate or indomethacin on rat testes. Evidence of testosterone independent effects. I. Andrologia. 1987 Nov-Dec;19(6):602-13. DOI:10.1111/j.1439-0272.1987.tb01908.x
[2] Jones RC. The effect of a luteinizing hormone releasing hormone (LRH) agonist (Wy-40,972), levonorgestrel, danazol and ovariectomy on experimental endometriosis in the rat. Acta Endocrinol (Copenh). 1984 Jun;106(2):282-8. DOI:10.1530/acta.0.1060282