trypanothione
trypanothione Basic information
- Product Name:
- trypanothione
- Synonyms:
-
- Trypanothione trifluoroacetate salt
- trypanothione disulfide
- Glycinamide, L-γ-glutamyl-L-cysteinyl-N-[3-[[4-[(L-γ-glutamyl-L-cysteinylglycyl)amino]butyl]amino]propyl]-, cyclic (2→2')-disulfide
- Trypanothione N1,N8-Bis(glutathionyl)-spermidine disulfide
- CAS:
- 96304-42-6
- MF:
- C27H47N9O10S2
- MW:
- 721.85
- Product Categories:
-
- amino
- Mol File:
- 96304-42-6.mol
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trypanothione Chemical Properties
- storage temp.
- Store at 0°C
- BRN
- 3645155
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trypanothione Usage And Synthesis
Uses
A major function of trypanothione is in the defence against oxidative stress. Trypanothione-dependent enzymes such as tryparedoxin peroxidase (TryP) reduce peroxides using electrons donated either directly from trypanothione, or via the redox intermediate tryparedoxin.
Definition
ChEBI: Trypanothione disulfide is the oxidized form of N1,N8-bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid Crithidia fasciculata.
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