norbergenin
norbergenin Basic information
- Product Name:
- norbergenin
- Synonyms:
-
- norbergenin
- (2R)-3,4,4aα,10bβ-Tetrahydro-3β,4α,8,9,10-pentahydroxy-2α-(hydroxymethyl)pyrano[3,2-c][2]benzopyran-6(2H)-one
- Pyrano[3,2-c][2]benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,9,10-pentahydroxy-2-(hydroxymethyl)-, (2R,3S,4S,4aR,10bS)-
- radical,norbergenin,antioxidant,Reactive Oxygen Species,bergenin,scavenging,inhibit,Inhibitor,derivative,superoxide
- norbergenin, 10 mM in DMSO
- CAS:
- 79595-97-4
- MF:
- C13H14O9
- MW:
- 314.24
- Mol File:
- 79595-97-4.mol
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norbergenin Chemical Properties
- Melting point:
- 248-249 °C
- Boiling point:
- 705.9±60.0 °C(Predicted)
- Density
- 1.799±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- form
- Solid
- pka
- 7.63±0.70(Predicted)
- color
- White to yellow
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norbergenin Usage And Synthesis
Uses
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC50 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging)[1].
References
[1] Takahashi H, et al. Synthesis and neuroprotective activity of bergenin derivatives with antioxidant activity. Bioorg Med Chem. 2003;11(8):1781-1788. DOI:10.1016/s0968-0896(02)00666-1
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