botryodiplodin
botryodiplodin Basic information
- Product Name:
- botryodiplodin
- Synonyms:
-
- botryodiplodin
- 1-(2-Hydroxy-3-methyltetrahydrofuran-4-yl)ethanone
- 4-Acetyl-2-hydroxy-3-methyltetrahydrofuran
- 4-Acetyltetrahydro-3-methylfuran-2-ol
- Ethanone, 1-[(3S,4R)-tetrahydro-5-hydroxy-4-methyl-3-furanyl]-
- Antibiotic PSX 1
- Cytostipin
- CAS:
- 27098-03-9
- MF:
- C7H12O3
- MW:
- 144.17
- Mol File:
- 27098-03-9.mol
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botryodiplodin Chemical Properties
- Melting point:
- 51°C
- Boiling point:
- 202.77°C (rough estimate)
- Density
- 1.0789 (rough estimate)
- refractive index
- 1.4850 (estimate)
- pka
- 12.79±0.60(Predicted)
- LogP
- 0.571 (est)
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botryodiplodin Usage And Synthesis
Uses
Botryodiplodin is a mycotoxin isolated from Penicillium roqueforti. Botryodiplodin inhibits the growth of some Gram-positive and Gram-negative bacteria and can also induce DNA-protein cross-links in mammalian cells, inhibiting the synthesis of DNA, RNA, and protein[1][2].
Definition
ChEBI: Botryodiplodin is a member of oxolanes.
References
[1] Moulé Y, et al. DNA-protein cross-linking by the mycotoxin, botryodiplodin, in mammalian cells[J]. Carcinogenesis, 1982, 3(2): 211-214. DOI:10.1093/carcin/3.2.211
[2] Moulé Y, et al. Mutagenicity of the mycotoxin botryodiplodin in the Salmonella typhimurium/microsomal activation test[J]. Environmental Mutagenesis, 1981, 3(3): 287-291. DOI:10.1002/em.2860030311