3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile Chemical Properties

Melting point:

193-195 °C(Solv: ethanol (64-17-5))

Boiling point:

588.3±50.0 °C(Predicted)

Density 

1.43±0.1 g/cm3(Predicted)

pka

10.67±0.70(Predicted)

3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile Usage And Synthesis

Uses

Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].

References

[1] Watanabe A, et al. Effect of TYB-2285 on antigen-induced histamine release from mouse bone marrow-derived persisting cells (P-cells) primed with interleukin-3-containing conditioned medium (IL3-CM). Gen Pharmacol. 1993 Sep;24(5):1207-11. DOI:10.1016/0306-3623(93)90370-d

3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile(123548-56-1)Related Product Information

• 4-Chlorobenzonitrile
• 3-AMINO-4-CHLOROBENZONITRILE
• 3,5-DIAMINOBENZONITRILE
• 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile