bursopoietin
bursopoietin Basic information
- Product Name:
- bursopoietin
- Synonyms:
-
- bursopoietin
- Bursin【chicken】
- L-Lys-L-His-Gly-NH2
- Bursin (avian) H-Lys-His-Gly-NH2
- Glycinamide, L-lysyl-L-histidyl-
- (2S)-2,6-diamino-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]hexanamide
- (S)-2,6-Diamino-N-((S)-1-((2-amino-2-oxoethyl)amino)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)hexanamide
- CAS:
- 60267-34-7
- MF:
- C14H25N7O3
- MW:
- 339.39
- Mol File:
- 60267-34-7.mol
bursopoietin Chemical Properties
- Boiling point:
- 872.5±65.0 °C(Predicted)
- Density
- 1.289±0.06 g/cm3(Predicted)
- pka
- 13.53±0.46(Predicted)
- form
- Solid
- color
- White to off-white
bursopoietin Usage And Synthesis
Description
Bursopoietin Cell differentiation agent in extracts of chicken bursa of fabricus.
Uses
Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2[1].
References
[1] Wang C, et al. Bursin-like peptide (BLP) enhances H9N2 influenza vaccine induced humoral and cell mediated immune responses. Cell Immunol. 2014 Nov-Dec;292(1-2):57-64. DOI:10.1016/j.cellimm.2014.09.003
[2] Audhya T, et al. Tripeptide structure of bursin, a selective B-cell-differentiating hormone of the bursa of fabricius. Science. 1986 Feb 28;231(4741):997-9. DOI:10.1126/science.3484838
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