Basic information Safety Supplier Related

bursopoietin

Basic information Safety Supplier Related

bursopoietin Basic information

Product Name:
bursopoietin
Synonyms:
  • bursopoietin
  • Bursin【chicken】
  • L-Lys-L-His-Gly-NH2
  • Bursin (avian) H-Lys-His-Gly-NH2
  • Glycinamide, L-lysyl-L-histidyl-
  • (2S)-2,6-diamino-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]hexanamide
  • (S)-2,6-Diamino-N-((S)-1-((2-amino-2-oxoethyl)amino)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)hexanamide
CAS:
60267-34-7
MF:
C14H25N7O3
MW:
339.39
Mol File:
60267-34-7.mol
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bursopoietin Chemical Properties

Boiling point:
872.5±65.0 °C(Predicted)
Density 
1.289±0.06 g/cm3(Predicted)
pka
13.53±0.46(Predicted)
form 
Solid
color 
White to off-white
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bursopoietin Usage And Synthesis

Description

Bursopoietin Cell differentiation agent in extracts of chicken bursa of fabricus.

Uses

Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2[1].

References

[1] Wang C, et al. Bursin-like peptide (BLP) enhances H9N2 influenza vaccine induced humoral and cell mediated immune responses. Cell Immunol. 2014 Nov-Dec;292(1-2):57-64. DOI:10.1016/j.cellimm.2014.09.003
[2] Audhya T, et al. Tripeptide structure of bursin, a selective B-cell-differentiating hormone of the bursa of fabricius. Science. 1986 Feb 28;231(4741):997-9. DOI:10.1126/science.3484838

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