Basic information Safety Supplier Related

phthalascidin

Basic information Safety Supplier Related

phthalascidin Basic information

Product Name:
phthalascidin
Synonyms:
  • phthalascidin
  • 7,13-Imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-14-carbonitrile, 5-(acetyloxy)-16-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-6,6a,7,13,14,16-hexahydro-8-hydroxy-9-methoxy-4,10,17-trimethyl-, (6aS,7R,13S,14R,16R)-
CAS:
236743-94-5
MF:
C36H34N4O8
MW:
650.68
Mol File:
236743-94-5.mol
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phthalascidin Usage And Synthesis

Enzyme inhibitor

This semisynthetic antitumor agent (FWfree-base = 650.69 g/mol), also known as Pt 650, binds to the minor groove of DNA and inhibits DNA topoisomerase I. Phthalascidin is prepared from ecteinascidin 743.

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