PERAKINE
PERAKINE Basic information
- Product Name:
- PERAKINE
- Synonyms:
-
- PERAKINE
- (13R)-13-Acetyloxy-7aα,2α,6α-ethan[1]yl[2]ylidene-1,2,3,4,6,7,7a,12bβ-octahydro-4α-methylindolo[2,3-a]quinolizine-3β-carbaldehyde
- (17R,20α)-19-Oxo-1,2-didehydro-1-demethyl-21β-methyl-18-norajmalan-17-ol acetate
- 18-Norajmalan-19-al, 17-(acetyloxy)-1,2-didehydro-1-demethyl-21-methyl-, (17R,20A,21B)-
- Aids003043
- Aids-003043
- Indole alkaloid
- Raucaffrine
- CAS:
- 4382-56-3
- MF:
- C21H22N2O3
- MW:
- 350.42
- Mol File:
- 4382-56-3.mol
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PERAKINE Chemical Properties
- Melting point:
- 186 °C
- Boiling point:
- 492.8±45.0 °C(Predicted)
- Density
- 1.59±0.1 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 5.38±0.70(Predicted)
- color
- White to off-white
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PERAKINE Usage And Synthesis
Description
This alkaloid has been shown to be identical with Perakine (q.v.).
Uses
Perakine is an alkaloid extracted from family of Rauvolfia plants which acts as an inhibitor of aldose reductase, a potent drug target for diabetes.
Definition
ChEBI: An indole alkaloid having a ajmalan-type skeleton and characterised by a 17alpha-acetoxy group, a 21beta-methyl group, loss of the 1-methyl group with associated unsaturation at N(1)2C(2), and a 20alph -formyl group in place of the 20beta-ethyl side-chain.
References
Khan, Khan, Siddiqui., Pakistan 1. Sci. Ind. Res., 8, 23 (1965)
PERAKINESupplier
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