Vitexia-glucoside
Vitexia-glucoside Basic information
- Product Name:
- Vitexia-glucoside
- Synonyms:
-
- Vitexia-glucoside
- Vitexin 4'-glucoside
- 4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-2-[4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-
- 4'-O-Glucosylvitexin
- Glucosylvitexin/Vitexin -4''-O-glucoside
- CAS:
- 38950-94-6
- MF:
- C27H30O15
- MW:
- 594.52
- Mol File:
- 38950-94-6.mol
Vitexia-glucoside Chemical Properties
- Boiling point:
- 937.3±65.0 °C(Predicted)
- Density
- 1.723±0.06 g/cm3 (20 ºC 760 Torr)
- form
- Solid
- pka
- 6.25±0.40(Predicted)
- color
- Light yellow to yellow
Vitexia-glucoside Usage And Synthesis
Chemical Properties
Light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from hawthorn.
Uses
Vitexia-glucoside has the effects of treating ischemic heart disease, lowering blood lipids and resisting cancer.
Definition
ChEBI: 4'-O-Glucosylvitexin is a member of flavonoids and a glycoside.
Biological Activity
Vitexin 4'-glucoside is a leaf flavonoid identified from Briza stricta.
Synthesis
60g of crude extract of hawthorn leaf was dissolved by adding 500mL of distilled water with ultrasonication, and the insoluble material was filtered out, and the filtrate flowed through the HPD-400 macroporous resin column at a flow rate of 3BV/h. After the adsorption was completed, the HPD-400 macroporous resin column was first fully eluted with distilled water at 5BV, and the first-stage eluent was collected, and after concentrated and lyophilized, 5.49g of chlorogenic acid analogs with a purity of 70.3% was obtained; The HPD- 400 macroporous resin column was then fully eluted with 5BV 50% ethanol aqueous solution, and the second stage eluent was collected, and the solvent was recovered by reduced-pressure distillation to obtain 19.32 g of total hawthorn leaf flavonoids with a purity of 59.7%; the total flavonoids of hawthorn leaf were solubilized with 50 mL of methanol, and purified by preparative chromatography using a {C18 column (50??250 mm, 10 ??m), 35/65 ( V/V) of 0.1% aqueous acetic acid/methanol}, the monomer eluent was collected separately, and after distillation under reduced pressure, 0.29 g of pungitin glucoside with 96.2% purity and 1.29 g of pungitin rhamnoside with 96.3% purity were obtained.
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