3-aminopiperidine-2,6-dione
3-aminopiperidine-2,6-dione Basic information
- Product Name:
- 3-aminopiperidine-2,6-dione
- Synonyms:
-
- 3-aminopiperidine-2,6-dione
- 2,6-Piperidinedione, 3-amino-
- 3-aminopiperidine-2,6-quinone
- 3-azanylpiperidine-2,6-dione
- alpha-Aminoglutarimide
- Glutamimide
- 3-Amino-2,6-piperidinedione
- pyroglutamine
- CAS:
- 2353-44-8
- MF:
- C5H8N2O2
- MW:
- 128.13
- EINECS:
- 1312995-182-4
- Mol File:
- 2353-44-8.mol
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3-aminopiperidine-2,6-dione Chemical Properties
- Melting point:
- 142-143℃
- Boiling point:
- 334.5±35.0 °C(Predicted)
- Density
- 1.243±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- pka
- 11.15±0.40(Predicted)
- InChI
- InChI=1S/C5H8N2O2/c6-3-1-2-4(8)7-5(3)9/h3H,1-2,6H2,(H,7,8,9)
- InChIKey
- NPWMTBZSRRLQNJ-UHFFFAOYSA-N
- SMILES
- N1C(=O)CCC(N)C1=O
- CAS DataBase Reference
- 2353-44-8
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3-aminopiperidine-2,6-dione Usage And Synthesis
Uses
3-Amino-piperidine-2,6-dione is used for studies on the hydrolytic degradation and primary metabolic pathway of thalidomide in animals and human liver microsomes. Thalidomide is a sedative drug used to treat morning sickness.
Definition
ChEBI: A dicarboximide that is piperidine-2,6-dione substituted at position 3 by an amino group.
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