1H-Benz[e]indolium, 2-[5-[3-[[6-[(6-aminohexyl)amino]-6-oxohexyl]-1,3-dihydro-1,1-dimethyl-6,8-disulfo-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-1,3-pentadien-1-yl]-1,1,3-trimethyl-6,8-disulfo-, inner salt Chemical Properties

pka

-0.276±0.40(predicted)

1H-Benz[e]indolium, 2-[5-[3-[[6-[(6-aminohexyl)amino]-6-oxohexyl]-1,3-dihydro-1,1-dimethyl-6,8-disulfo-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-1,3-pentadien-1-yl]-1,1,3-trimethyl-6,8-disulfo-, inner salt Usage And Synthesis

Uses

Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling[1].

References

[1] Yasuaki Anami, et al. Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors. Cell Rep. 2022 May 24;39(8):110839. DOI:10.1016/j.celrep.2022.110839