5-BROMO-2-[(4-METHOXYCARBONYL)PHENOXY]PYRIMIDINE
5-BROMO-2-[(4-METHOXYCARBONYL)PHENOXY]PYRIMIDINE Basic information
- Product Name:
- 5-BROMO-2-[(4-METHOXYCARBONYL)PHENOXY]PYRIMIDINE
- Synonyms:
-
- 5-BROMO-2-[(4-METHOXYCARBONYL)PHENOXY]PYRIMIDINE
- Methyl 4-(5-bromopyrimidin-2-yloxy)benzoate
- 4-(5-Bromo-pyrimidin-2-yloxy)-benzoic acid methyl ester
- 4-[(5-bromo-2-pyrimidinyl)oxy]Benzoic acid methyl ester
- Methyl 4-((5-bromopyrimidin-2-yl)
- Benzoic acid, 4-[(5-bromo-2-pyrimidinyl)oxy]-, methyl ester
- 5-bromo-2-[(4-methoxycarbonyl)phenoxy]pyrimidine, CAS 926304-76-9
- CAS:
- 926304-76-9
- MF:
- C12H9BrN2O3
- MW:
- 309.12
- Mol File:
- 926304-76-9.mol
More
Less
5-BROMO-2-[(4-METHOXYCARBONYL)PHENOXY]PYRIMIDINE Chemical Properties
- storage temp.
- Sealed in dry,Room Temperature
More
Less
5-BROMO-2-[(4-METHOXYCARBONYL)PHENOXY]PYRIMIDINE Usage And Synthesis
Synthesis
32779-36-5
99-76-3
926304-76-9
Methyl 4-hydroxybenzoate (260 mg, 1.71 mmol) was dissolved in N,N-dimethylformamide (DMF, 25 mL) at room temperature, followed by the addition of 60% sodium hydride (NaH, 75 mg, 1.9 mmol). The reaction mixture was stirred for 30 min. After that, 5-bromo-2-chloropyrimidine (300 mg, 1.55 mmol) was added and the reaction system was heated to 130 °C and the reaction was maintained for 0.5 hours. After standard post-treatment and purification steps, the target product methyl 4-(5-bromopyrimidin-2-yloxy)benzoate (428 mg, 89% yield) was obtained.
References
[1] Patent: WO2007/22371, 2007, A2. Location in patent: Page/Page column 65
5-BROMO-2-[(4-METHOXYCARBONYL)PHENOXY]PYRIMIDINESupplier
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
Wuhan Chemwish Technology Co., Ltd
- Tel
- 86-027-67849912
- sales@chemwish.com
Shanghai Witofly Chemical Co.,Ltd
- Tel
- sales@witofly.com
AN PharmaTech Co Ltd
- Tel
- 86(21)68097365
- sales@anpharma.net
SanoChem (Chengdu) Tech. Co., Ltd.
- Tel
- 28-87999436 02887999436
- sales@sano-chem.com