1,8-NAPHTHALALDEHYDIC ACID Chemical Properties

Melting point:

160-167 °C

Boiling point:

441.2±18.0 °C(Predicted)

Density 

1.354±0.06 g/cm3(Predicted)

pka

2?+-.0.10(Predicted)

form 

Powder

color 

Cream

CAS DataBase Reference

5811-87-0

EPA Substance Registry System

8-Formyl-1-naphthalenecarboxylic acid (5811-87-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HS Code 

29122900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

1,8-NAPHTHALALDEHYDIC ACID Usage And Synthesis

Chemical Properties

Cream powder

Uses

1,8-Naphthalaldehydic acid may be used in the synthesis of fused bicyclic lactams, such as:

• 2,3,5,11b-tetrahydrobenz[de][1,3]oxazolo[3,2-a]isoquinolin-5-one
• 2,3,4,12b-tetrahydro-6H-benz[de][1,3]oxazino[3,2-a]isoquinolin-6-one
• 2,3,4,5,7,13b-hexahydrobenz[de][1,3]oxazepino[3,2-a]isoquinolin-7-one
• 1,2,3,11b-tetrahydro-5H-benz[de]imidazo[3,2-a]isoquinolin-5-one
• 1,2,3,4,6,12b-hexahydrobenzo[de]pyrimido[3,2-a]isoquinolin-7-one
• 1,2,3,4,5,13b-hexahydro-7H-benzo[de]1,3-diazepino[3,2-a]isoquinolin-7-one
• 7H-benzo[de]benzimidazo[3,2-a]isoquinolin-7-one
• 2,3,5,11b-tetrahydrobenzo[de]thiazolo[3,2-a]isoquinolin-5-one
• (9S,9R)-methyl 5-oxo[2,3,5,11b]-tetrahydrobenz[de]oxazolo[3,2-a]isoquinoline-3-carboxylate
• (3R,11bS)-3-phenyl-2,3,5,11b-tetrahydrobenz[de][1,3]oxazolo[2,3-a]isoquinolin-5-one

Synthesis Reference(s)

Journal of Medicinal Chemistry, 35, p. 823, 1992 DOI: 10.1021/jm00083a005

1,8-NAPHTHALALDEHYDIC ACID(5811-87-0)Related Product Information

• 1,8-Naphthalic anhydride
• 1,4,5,8-Naphthalenetetracarboxylic acid
• 3,4,9,10-Perylenetetracarboxylic dianhydride
• 4-Nitronaphthalene-1,8-dicarboxylic anhydride
• 1,8-NAPHTHALIC ACID
• 4-Chloro-1,8-naphthalic anhydride
• 1,4,5,8-Naphthalenetetracarboxylic dianhydride
• 8-CARBOXYNAPHTHALENE-1-CARBOXAMIDE
• 3-NITRO-1,8-NAPHTHALIC ANHYDRIDE
• 4-Bromo-1,8-naphthalic anhydride
• 3-Hydroxy-1,8-naphthalic anhydride
• 5-AMINO-BENZO[DE]ISOCHROMENE-1,3-DIONE
• 4-Amino-1,8-naphthalic anhydride
• 1,8-NAPHTHALALDEHYDIC ACID
• 4-AMINO-3 6-DISULFO-1 8-NAPHTHALIC
• 6-[(2-HYDROXYETHYL)THIO]-1H,3H-NAPHTHO[1,8-CD]PYRAN-1,3-DIONE
• 1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE -4-SULPHO POTASSIUM SALT