1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE Chemical Properties

Melting point:

48-49°C

Boiling point:

156-158 °C(Press: 17 Torr)

Density 

1.506±0.06 g/cm3(Predicted)

pka

7.28±0.40(Predicted)

Safety Information

HazardClass 

IRRITANT

HS Code 

2914790090

1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE Usage And Synthesis

Uses

1-(4-Bromo-2-hydroxyphenyl)-1-propanone is a useful compound for preparation of indazoles.

Preparation

Preparation by Friedel–Crafts acylation of m-bromophenol with propionyl chloride in the presence of aluminium chloride in refluxing ethylene dichloride for 2 h (78%)
Also obtained by Fries rearrangement of 3-bromophenyl propionate in the presence of aluminium chloride at 50° for 3 h (47%).

1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE(17764-92-0)Related Product Information

• 1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE
• 7-Bromo-4-oxo-4H-chromene-3-carbaldehyde
• 6-BROMOCHROMONE-3-PROPIONIC ACID
• 5-BROMO-2-PROPIONYLPHENYL METHANESULFONATE
• 8-BROMO-3,4-DIHYDRO-1-BENZOXEPIN-5(2H)-ONE
• N-BOC-7-BROMO-4-OXO-3,4-DIHYDRO-1''H-SPIRO[CHROMENE-2,4''-PIPERIDINE]
• 7-bromochroman-4-one