6,7',12-Trimethoxy-2,2'-dimethylthalman-6'-ol
6,7',12-Trimethoxy-2,2'-dimethylthalman-6'-ol Basic information
- Product Name:
- 6,7',12-Trimethoxy-2,2'-dimethylthalman-6'-ol
- Synonyms:
-
- 6,7',12-Trimethoxy-2,2'-dimethylthalman-6'-ol
- Thalmine
- CAS:
- 7682-65-7
- MF:
- C35H36N2O6
- MW:
- 580.677
- Mol File:
- 7682-65-7.mol
6,7',12-Trimethoxy-2,2'-dimethylthalman-6'-ol Chemical Properties
- Melting point:
- 253 C (dec.).
6,7',12-Trimethoxy-2,2'-dimethylthalman-6'-ol Usage And Synthesis
Description
This alkaloid from Thalictrum minus was originally given the empirical formula C2oH2303N, later altered to that given above. It forms colourless crystals from a mixture of CHC13 and EtOH and is laevorotatory with [α]D - 64.5°. The salts and derivatives are crystalline but normally decompose before melting: the hydrochloride, m.p. 147-157°C (dec.); perchlorate, decomposing at 238-241°C and the methiodide, decomposing at 250°C. The o-acetate has [α]D - 219°. Three methoxyl groups, a phenolic hydroxyl group and two methylimino groups are present
Definition
ChEBI: Thalmine is a member of isoquinolines and a bisbenzylisoquinoline alkaloid.
References
Yunusov, Progressov.,J. Gen. Chem., USSR, 20, 1151 (1950)
Telezhenetskaya, Ismailov, Yunusov., Khim. Prir. Soedin., 2, 107 (1966)
Baldas et ai., Tetrahedron Lett., 6315 (1968)