2-Mercapto-2-phenylacetic acid Chemical Properties

Melting point:

64-65 °C

Boiling point:

145 °C(Press: 4 Torr)

Density 

1.277±0.06 g/cm3(Predicted)

pka

3.21±0.10(Predicted)

form 

Solid

color 

White to off-white

2-Mercapto-2-phenylacetic acid Usage And Synthesis

Description

Thiomandelic acid is an Anti-Bacterial Agent.

Uses

Thiomandelic acid is a broad spectrum inhibitor of Zinc -lactamases[1].

References

[1] C Mollard, et al. Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. J Biol Chem. 2001 Nov 30;276(48):45015-23. DOI:10.1074/jbc.M107054200
[2] Christian Damblon, et al. The inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding. J Biol Chem. 2003 Aug 1;278(31):29240-51. DOI:10.1074/jbc.M301562200