Basic information Safety Supplier Related

1-N-Ethoxycarbonyl-3-pyrrolidone

Basic information Safety Supplier Related

1-N-Ethoxycarbonyl-3-pyrrolidone Basic information

Product Name:
1-N-Ethoxycarbonyl-3-pyrrolidone
Synonyms:
  • 1-N-ETHOXYCARBONYL-3-PYRROLIDONE
  • N-(Ethoxy carboNyl)-3-pyrrolidoNe
  • 1-ETHOXYCARBONYL-3-PYRROLIDONE
  • 1-Ethoxycabonyl-3-Pyrrolidone
  • 3-OXO-PYRROLIDINE-1-CARBOXYLIC ACID ETHYL ESTER
  • 1-Pyrrolidinecarboxylic acid, 3-oxo-, ethyl ester
  • ethyl 3-oxopyrrolidine-1-carboxylate
  • Ethyl 3-oxopyrrolidine-1-...
CAS:
14891-10-2
MF:
C7H11NO3
MW:
157.17
Product Categories:
  • Pyrrole&Pyrrolidine&Pyrroline
Mol File:
14891-10-2.mol
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1-N-Ethoxycarbonyl-3-pyrrolidone Chemical Properties

Boiling point:
122-132 °C(Press: 12 Torr)
Density 
1.205±0.06 g/cm3(Predicted)
pka
-1.79±0.20(Predicted)
CAS DataBase Reference
14891-10-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
36/37/38-36-22
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
2933998090
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1-N-Ethoxycarbonyl-3-pyrrolidone Usage And Synthesis

Chemical Properties

Boiling point 100-107 ℃ (0.4kPa).

Uses

1-N-Ethoxycarbonyl-3-pyrrolidone can be used as a pharmaceutical intermediate.

Synthesis

Glycine is added to acrylonitrile to obtain N-cyanoethylglycine, which is esterified with ethanol and condensed with methyl ethyl chloroformate to form N-ethoxycarbonyl-N-ethoxycarbonylethylglycine ethyl ester, which is then cyclized , hydrolysis and elimination to obtain 1-ethoxycarbonylpyrrolidin-3-one.

1-N-Ethoxycarbonyl-3-pyrrolidone Preparation Products And Raw materials

Raw materials

1-N-Ethoxycarbonyl-3-pyrrolidoneSupplier

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