Basic information Safety Supplier Related

FTY720-d4 Hydrochloride

Basic information Safety Supplier Related

FTY720-d4 Hydrochloride Basic information

Product Name:
FTY720-d4 Hydrochloride
Synonyms:
  • 2-AMino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol-d4 Hydrochloride
  • FingoliMod-d4 Hydrochloride
  • Fingolimod-d4 HCl
  • FTY720-d4 Hydrochloride
  • 2-amino-1,1,3,3-tetradeuterio-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol
  • Fingolimod-d4 HCl (1,3-propane-1,1,3,3-d4-diol)
  • [2H4]-Fingolimod Hydrochloride
  • [2H4]-Fingolimod HCl
CAS:
1346604-90-7
MF:
C19H34ClNO2
MW:
343.93176
Product Categories:
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Metabolites & Impurities
  • Aromatics, Inhibitors, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
1346604-90-7.mol
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FTY720-d4 Hydrochloride Chemical Properties

Melting point:
105-107°C
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White
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FTY720-d4 Hydrochloride Usage And Synthesis

Chemical Properties

White Solid

Uses

A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).

FTY720-d4 HydrochlorideSupplier

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