Basic information Safety Supplier Related

4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER

Basic information Safety Supplier Related

4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER Basic information

Product Name:
4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER
Synonyms:
  • DABCYL ACID, SE
  • DABCYL, SE
  • DABCYL SUCCINIMIDE ESTER
  • DABCYL-N-SUCCINIMIDYL ESTER
  • DABCYL-OSU
  • DABCYL-NHS
  • -2,5-Dioxopyrrolidin-1-yl 4-((4-(dimethylamino)
  • N-Succinimidyl 4-[4-(dimethylamino)phenylazo]benzoate≥ 98%(HPLC)
CAS:
146998-31-4
MF:
C19H18N4O4
MW:
366.37
Product Categories:
  • Fluorescent Dyes
Mol File:
146998-31-4.mol
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4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER Chemical Properties

Melting point:
242 °C(dec.)
Boiling point:
550.7±60.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO.
pka
3.28±0.10(Predicted)
form 
powder to crystal
color 
Light yellow to Amber to Dark green
Sensitive 
Moisture Sensitive
InChIKey
IBOVDNBDQHYNJI-QZQOTICOSA-N
CAS DataBase Reference
146998-31-4
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Safety Information

Safety Statements 
24/25
RIDADR 
3234
WGK Germany 
3
10-21
HS Code 
29280000

MSDS

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4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER Usage And Synthesis

Uses

Non-Fluorescent probe for labeling proteins or peptides

Uses

4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester is a useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies. It is also used for N-terminal modification of peptides in automated synthesis.

Definition

ChEBI: Dabcyl SE dye is a pyrrolidinone and a monoazo compound. It has a role as a fluorochrome.

4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTERSupplier

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