4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER
4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER Basic information
- Product Name:
- 4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER
- Synonyms:
-
- DABCYL ACID, SE
- DABCYL, SE
- DABCYL SUCCINIMIDE ESTER
- DABCYL-N-SUCCINIMIDYL ESTER
- DABCYL-OSU
- DABCYL-NHS
- -2,5-Dioxopyrrolidin-1-yl 4-((4-(dimethylamino)
- N-Succinimidyl 4-[4-(dimethylamino)phenylazo]benzoate≥ 98%(HPLC)
- CAS:
- 146998-31-4
- MF:
- C19H18N4O4
- MW:
- 366.37
- Product Categories:
-
- Fluorescent Dyes
- Mol File:
- 146998-31-4.mol
4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER Chemical Properties
- Melting point:
- 242 °C(dec.)
- Boiling point:
- 550.7±60.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO.
- pka
- 3.28±0.10(Predicted)
- form
- powder to crystal
- color
- Light yellow to Amber to Dark green
- Sensitive
- Moisture Sensitive
- InChIKey
- IBOVDNBDQHYNJI-QZQOTICOSA-N
- CAS DataBase Reference
- 146998-31-4
MSDS
- Language:English Provider:SigmaAldrich
4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER Usage And Synthesis
Uses
Non-Fluorescent probe for labeling proteins or peptides
Uses
4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester is a useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies. It is also used for N-terminal modification of peptides in automated synthesis.
Definition
ChEBI: Dabcyl SE dye is a pyrrolidinone and a monoazo compound. It has a role as a fluorochrome.
4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTERSupplier
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4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER(146998-31-4)Related Product Information
- 2,6-Dimethylaniline
- 2,6-Lutidine
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- 6-CARBOXY-X-RHODAMINE
- 6-JOE SE
- 5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*
- 7-Methoxycoumarin-4-acetic acid
- 5-ROX, SE
- 5(6)-CARBOXY-X-RHODAMINE FOR FLUOR-
- 1,5-EDANS
- 6-ROX, SE
- 5(6)-CARBOXY-X-RHODAMINE-N-HYDROXYSUCCINIMIDE ESTER
- 4-DIMETHYLAMINO-4'-METHYLAZOBENZENE
- 4-(PHENYLAZO)BENZOIC ACID
- 4-DIMETHYLAMINOAZOBENZENE-4'-CARBOXYLIC ACID
- 4-((4-(DIMETHYLAMINO)PHENYL)AZO)BENZOIC ACID, SUCCINIMIDYL ESTER
- MANCYL-SE