ISOVALERYL-PHE-NLE-STA-ALA-STA-OH
ISOVALERYL-PHE-NLE-STA-ALA-STA-OH Basic information
- Product Name:
- ISOVALERYL-PHE-NLE-STA-ALA-STA-OH
- Synonyms:
-
- ISOVALERYL-PHE-NLE-STA-ALA-STA-OH
- SR 42128
- N-(3-Methyl-1-oxobutyl)-L-phenylalanyl-L-norleucyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-L-alaninamide
- Iva-Phe-Nle-Sta-Ala-Sta-OH
- L-Alaninamide, N-(3-methyl-1-oxobutyl)-L-phenylalanyl-L-norleucyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-
- CAS:
- 98092-14-9
- MF:
- C39H65N5O9
- MW:
- 747.96
- Product Categories:
-
- Pepetides
- peptides
- Mol File:
- 98092-14-9.mol
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ISOVALERYL-PHE-NLE-STA-ALA-STA-OH Chemical Properties
- storage temp.
- -15°C
- Sequence
- {Isovaleryl}-Phe-{Nle}-{Sta}-Ala-{Sta}
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ISOVALERYL-PHE-NLE-STA-ALA-STA-OH Usage And Synthesis
Uses
SR 42128 is a potent renin inhibitor. SR 42128 potently inhibits primate renins whereas other animal renins are much less inhibited[1].
References
[1] M De Claviere, et al. In vitro and in vivo inhibition of human and primate renin by a new potent renin inhibitor: SR 42128. J Cardiovasc Pharmacol. 1985:7 Suppl 4:S58-61. DOI:10.1097/00005344-198507004-00012
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