BAY-721973
BAY-721973 Basic information
- Product Name:
- BAY-721973
- Synonyms:
-
- BAY-721973
- 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-(hydroxymethyl)-
- Sorafenib metabolite M3
- UNII-83F1Z938Q0
- CAS:
- 1380310-94-0
- MF:
- C21H16ClF3N4O4
- MW:
- 480.82
- Mol File:
- 1380310-94-0.mol
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BAY-721973 Chemical Properties
- Boiling point:
- 561.3±50.0 °C(Predicted)
- Density
- 1.516±0.06 g/cm3(Predicted)
- pka
- 12.21±0.46(Predicted)
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BAY-721973 Usage And Synthesis
Uses
N-Hydroxymethylsorafenib is a Sorafenib (HY-10201) metabolite, and can be used for research of metabolite of Sorafenib[1].
References
[1] Ghassabian S, et al. Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites. Biochem Pharmacol. 2012 Jul 15;84(2):215-23. DOI:10.1016/j.bcp.2012.04.001