msx-130
msx-130 Basic information
- Product Name:
- msx-130
- Synonyms:
-
- msx-130
- MSX-130; MSX 130; MSX130
- 1H-Imidazole, 2,2'-(1,4-phenylene)bis[4,5-diphenyl-
- 1,4-bis(4,5-diphenyl-1H-imidazol-2-yl)benzene
- CXCR4,MSX130,metastasis,Inhibitor,antagonist,CXC chemokine receptors,CXCR,MSX-130,cancer,inhibit
- CAS:
- 4051-59-6
- MF:
- C36H26N4
- MW:
- 514.62
- Mol File:
- 4051-59-6.mol
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msx-130 Chemical Properties
- solubility
- DMSO:3.0(Max Conc. mg/mL);5.83(Max Conc. mM)
- form
- A solid
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msx-130 Usage And Synthesis
Biological Activity
MSX-130 is a CXCR4 antagonist. It inhibits tumor metastasis.
in vitro
The CXC chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization.
target
| CXCR4
|
msx-130Supplier
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com
Shanghai Chaolan Chemical Technology Center
- Tel
- QQ:65489617 15618227136
- info@SuperLan-chem.com
Beijing Solarbio Science & Tecnology Co., Ltd.
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com