Azeliragon HCl
Azeliragon HCl Basic information
- Product Name:
- Azeliragon HCl
- Synonyms:
-
- Azeliragon HCl
- Azeliragon dihydrochloride
- Azeliragon HCl (TTP488
- Azeliragon hydrochloride
- TTP488 HCl
- CAS:
- 1284150-65-7
- MF:
- C32H39Cl2N3O2
- MW:
- 568.58
- Mol File:
- 1284150-65-7.mol
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Azeliragon HCl Usage And Synthesis
Description
Azeliragon, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.
Uses
3-(4-(2-Butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine Hyrochloride acts as a reagent in the preparation of imidazoles for the treatment of RAGE-mediated diseases and pharmacokinetics.
Azeliragon HClSupplier
ShangHai Biochempartner Co.,Ltd
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- 17754423994 17754423994
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TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
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InvivoChem
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- +1-708-310-1919 +1-13798911105
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DC Chemicals
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- 021-58447131 13564518121
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Changzhou Furuisi Biotechnology Co., Ltd
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- 0519-85524369
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