2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT Chemical Properties

Boiling point:

821.6±75.0 °C(Predicted)

Density 

2.15±0.1 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

DMSO: 1.1 mg/mL

pka

1.83±0.10(Predicted)

Safety Information

WGK Germany 

3

2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT Usage And Synthesis

Uses

MRS 2179 ammonium salt hydrate has been used as a P2Y1 receptor antagonist in porcine coronary small arteries, endothelial cells, and hippocampal astrocytes.

Biological Activity

A competitive antagonist at P2Y 1 receptors (K B = 100 nM). Selective over P2X 1 (IC 50 = 1.15 μ M), P2X 3 (IC 50 = 12.9 μ M), P2X 2 , P2X 4 , P2Y 2 , P2Y 4 and P2Y 6 receptors.

Biochem/physiol Actions

MRS 2179 resists localized venous thrombosis and is useful in treating thrombotic syndromes due to its platelet aggregation inhibition functionality.

2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT(101204-49-3)Related Product Information

• 2'-DEOXYADENOSINE 3'-MONOPHOSPHATE SODIUM SALT
• 2'-DEOXYADENOSINE 5'-MONOPHOSPHATE SODIUM SALT
• 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT