PHLOROGLUCIDE Chemical Properties

Melting point:

300 °C

Boiling point:

529.5±40.0 °C(Predicted)

Density 

1.594±0.06 g/cm3(Predicted)

storage temp. 

Dark Room

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Powder

pka

8.63±0.40(Predicted)

color 

Yellow to brown

Sensitive 

Light Sensitive

BRN 

3324960

Stability:

Hygroscopic

InChI

InChI=1S/C12H10O5/c13-7-1-6(2-8(14)3-7)12-10(16)4-9(15)5-11(12)17/h1-5,13-17H

InChIKey

KICYRZIVKKYRFS-UHFFFAOYSA-N

SMILES

C1(C2=CC(O)=CC(O)=C2)=C(O)C=C(O)C=C1O

CAS DataBase Reference

491-45-2

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-41

Safety Statements 

24/25-39-26

WGK Germany 

WGK 3

HS Code 

29072900

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Dam. 1

MSDS

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PHLOROGLUCIDE Usage And Synthesis

Chemical Properties

Yellowish to brown powder

Uses

Phloroglucide acts as a potential corrosion inhibitor of aluminum 2024 when combined in a hybrid flake composite with the metal. It is also a derivative of Phlorglucinol (P340000), an antispasmodic.

Synthesis

Step 1: m-triphenol (47.6 mol, 6 kg) was added to 24 liters of trifluoroacetic acid and stirred under heated reflux for 20 hours. Step 2: 15 liters of trifluoroacetic acid are evaporated under reduced pressure to give a residual solid. Step 3: 10 liters of dichloromethane were added to the residual solids, stirred to form a homogeneous slurry, filtered, and the solids were washed with dichloromethane to dry 5 kg of a pinkish-reddish crude, as shown in the HPLC plot of the crude in Fig. 1. Step 4: Take 2 kg of the crude product, add 20 liters of water, adjust the pH to 8 to 9 with sodium carbonate and stir under heated reflux for 18 hours, cool to room temperature, filter out the solids, and dry to yield 1.5 kg of light earthy yellow solid product.

PHLOROGLUCIDE(491-45-2)Related Product Information

• 5-Bromo-1,3-benzenediol
• 2,4,6-Triformylphloroglucinol
• 4-Bromoresorcinol
• Phloroglucinol dihydrate
• Phloroglucinol
• PHLOROGLUCIDE HYDRATE
• TETRAPHLORETHOL A
• PHLOROGLUCIDE