ETHYL 2-METHOXYPHENOXYACETATE Chemical Properties

Boiling point:

114-117°C 10mm

Density 

1.103

refractive index 

1.5130 to 1.5170

Flash point:

118℃

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

color 

Colorless to Light yellow

CAS DataBase Reference

13078-21-2

Safety Information

HS Code 

2918.99.5000

MSDS

• Language:English Provider:ALFA

ETHYL 2-METHOXYPHENOXYACETATE Usage And Synthesis

Synthesis

The general procedure for the synthesis of ethyl 2-methoxyphenoxyacetate from ethyl bromoacetate and guaiacol was as follows: first, erytftro-1-(3,4-dimethoxyphenyl)-2 -(2-methoxyphenoxy)-1,3-propanediol (2g). The spectral data of the compound were in agreement with literature reports as follows:1H NMR (400 MHz, CDCl3) δ 7.07 (ddd, J = 8.2, 7.2, 1.6 Hz, 1H), 7.02-6.84 (m, 5H), 6.82 (d, J = 8.2 Hz, 1H), 4.98 (bt, J = 4.8 Hz, 1H), 4.16 (ddd, J = 6.0, 4.8, 3.5 Hz, 1H), 3.95-3.90 (m, 1H), 3.87 (s, 3H), 3.86 (s, 6H), 3.66 (ddd, J = 12.0, 7.2, 3.5 Hz, 1H), 2.87 ppm (bs, 1H). hrms (ei) C18H22O6Na [M + Na]+ Calculated value 357.1314, measured value 357.1311.

References

[1] Organic Letters, 2016, vol. 18, # 19, p. 5166 - 5169
[2] Chemistry - A European Journal, 2011, vol. 17, # 49, p. 13877 - 13882
[3] Green Chemistry, 2017, vol. 19, # 19, p. 4538 - 4543
[4] Journal of Organic Chemistry, 2010, vol. 75, # 19, p. 6549 - 6562
[5] Journal of the American Chemical Society, 2013, vol. 135, # 17, p. 6415 - 6418

ETHYL 2-METHOXYPHENOXYACETATE(13078-21-2)Related Product Information

• ETHYL 2-METHOXYPHENOXYACETATE
• 4-FORMYL-2-METHOXY-PHENOXY-ACETIC ACID ETHYL ESTER
• 2-METHOXYPHENOXYACETIC ACID
• (4-BROMO-2-FORMYL-6-METHOXY-PHENOXY)-ACETIC ACID ETHYL ESTER
• ETHYL 2-(2-METHOXY-6-[(METHOXYIMINO)METHYL]PHENOXY)ACETATE
• ETHYL 1,4-BENZODIOXAN-2-CARBOXYLATE
• ethyl 2-(2-ethoxyphenoxy)acetate
• ETHYL 2-(4-CHLORO-2-METHOXY-6-[(METHOXYIMINO)METHYL]PHENOXY)ACETATE
• ETHYL 2-(4-BROMO-2-METHOXY-6-([(4-METHOXYPHENYL)IMINO]METHYL)PHENOXY)ACETATE
• ETHYL 2-(4-BROMO-2-METHOXY-6-[(PHENYLIMINO)METHYL]PHENOXY)ACETATE
• AKOS B005143
• ETHYL 2-(4-BROMO-2-METHOXY-6-[(METHOXYIMINO)METHYL]PHENOXY)ACETATE
• ETHYL 2-[4-BROMO-2-METHOXY-6-(([3-(TRIFLUOROMETHYL)PHENYL]IMINO)METHYL)PHENOXY]ACETATE
• AKOS B029853
• (4-ALLYL-2-METHOXY-PHENOXY)-ACETIC ACID ETHYL ESTER
• ETHYL 2-(4-BROMO-2-([(3-CHLOROPHENYL)IMINO]METHYL)-6-METHOXYPHENOXY)ACETATE
• ETHYL 2-(4-BROMO-2-([(4-CHLOROPHENYL)IMINO]METHYL)-6-METHOXYPHENOXY)ACETATE
• ETHYL 2-(4-BROMO-2-[(HYDROXYIMINO)METHYL]-6-METHOXYPHENOXY)ACETATE