D(+)-Pipecolinic acid Chemical Properties

Melting point:

272 °C(lit.)

alpha 

26.5 º (c=5,water 25 ºC)

Boiling point:

239.22°C (rough estimate)

Density 

1.1426 (rough estimate)

refractive index 

1.4300 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)

pka

2.28(at 25℃)

form 

Crystalline Powder

color 

White to off-white

optical activity

[α]25/D +27°, c = 1 in H2O

Water Solubility 

soluble

BRN 

81094

InChIKey

HXEACLLIILLPRG-RXMQYKEDSA-N

CAS DataBase Reference

1723-00-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

WGK Germany 

3

HS Code 

29333990

MSDS

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D(+)-Pipecolinic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

Pipecolic acid is involved in synaptic transmission in the central nervous system.

Definition

ChEBI: D-pipecolic acid is the D-enantiomer of pipecolic acid. It has a role as a human metabolite. It is a conjugate base of a D-pipecolate. It is an enantiomer of a L-pipecolic acid.

Purification Methods

D-Pipecolinic acid recrystallises as platelets from EtOH and is soluble in H2O. The hydrochloride has m 256-257o(dec) from H2O and [] D25 +10.8o (c 2, H2O). [cf p 422, Lukés et al. Collect Czech Chem Commun 22 286 1957, Bayerman Recl Trav Chim Pays-Bas 78 134 1959, Asher et al. Tetrahedron Lett 22 141 1981, Beilstein 22/1 V 220.]

D(+)-Pipecolinic acid(1723-00-8)Related Product Information

• Stearic acid
• Folic acid
• Ethyl 2-(Chlorosulfonyl)acetate
• Citric acid
• Thalidomide
• Haloperidol
• Ascoric Acid
• Diphenoxylate
• D-HOMOPROLINE METHYL ESTER HYDROCHLORIDE,D-HOMOPROLINE-OME HCL
• Everolimus
• BOC-DL-HOMOPROLINE,N-ALPHA-T-BUTOXYCARBONYL-DL-HOMOPROLINE
• Zabicipril
• Rapamycin
• Pimecrolimus
• Tacrolimus
• L-HOMOPROLINE METHYL ESTER HYDROCHLORIDE,HOMOPROLINE-OME HCL
• FMOC-L-PIPECOLIC ACID
• 2,5-DIBROMOPIPERIDINE