6-methylpurine riboside Chemical Properties

Melting point:

209-210 °C

Boiling point:

590.4±60.0 °C(Predicted)

Density 

1.81±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

pka

13.13±0.70(Predicted)

form 

Solid

color 

White to off-white

InChI

InChI=1/C11H14N4O4/c1-5-7-10(13-3-12-5)15(4-14-7)11-9(18)8(17)6(2-16)19-11/h3-4,6,8-9,11,16-18H,2H2,1H3/t6-,8-,9-,11-/s3

InChIKey

FIGBCBGMUIGJBD-SOMIAQKHNA-N

SMILES

N1(C=NC2C(C)=NC=NC1=2)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 |&1:10,11,13,15,r|

Safety Information

Hazard Codes 

T

Risk Statements 

23/24/25

Safety Statements 

36/37/39-45

6-methylpurine riboside Usage And Synthesis

Description

6-Methylpurine-β-D-riboside (β-D-MPR; 6-methylpurine riboside), an antibiotic isolated from culture broths of the basidiomycetes fungi Collybia dryophilia and Collybia maculata, has antifungal, antiviral and antitumor activity. β-D-MPR is an excellent substrate of mammalian adenosine deaminase (ADA), and its mechanism of activation in tumor cells presumably relates to its interaction with this enzyme [1].

References

[1] Sufrin, J . "Improved Synthesis of β-D-6-Methylpurine Riboside and Antitumor Effects of the β-D- and α-D-Anomers." Molecules 10(2005).

6-methylpurine riboside(14675-48-0)Related Product Information

• 6-Methylpurine
• 6-methylpurine riboside