Pendulone
Pendulone Basic information
- Product Name:
- Pendulone
- Synonyms:
-
- Pendulone
- 2,5-Cyclohexadiene-1,4-dione, 5-(3,4-dihydro-7-hydroxy-2H-1-benzopyran-3-yl)-2,3-dimethoxy-
- CAS:
- 69359-09-7
- MF:
- C17H16O6
- MW:
- 316.31
- Mol File:
- 69359-09-7.mol
Pendulone Usage And Synthesis
Uses
Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 μM. Pendulone also has antileishmanial, antibacterial and anticancer activity[1][2].
Definition
ChEBI: Pendulone is an isoflavonoid.
in vivo
Pendulone shows potent anti-tumor-promoting activity for an in vivo two-stage carcinogenesis test of mouse skin using 7,12-dimethylbenz[a]-anthracene and TPA[3].
IC 50
Plasmodium; Leishmania
References
[1] Qingxi Su, et al. Antiplasmodial Isoflavanes and Pterocarpans from Apoplanesia paniculata. Planta Med. 2015 Aug;81(12-13):1128-32. DOI:10.1055/s-0035-1546036
[2] Aziz A Rahman, et al. Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. Nat Prod Commun. 2011 Nov;6(11):1645-50. PMID:22224279
[3] T Konoshima, et al. Anti-tumor promoting activities of isoflavonoids from Wistaria brachybotrys. Biol Pharm Bull. 1997 Aug;20(8):865-8. DOI:10.1248/bpb.20.865
PenduloneSupplier
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
- Tel
- 18607101326 15172504745
- aileen@chemfaces.com
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
- Tel
- 028-028-85370565-229-229 18080489829
- 18080489829@163.com