17β-Estradiol 3-O-Sulfate SodiuM Salt Chemical Properties

Melting point:

207 °C

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-40

Safety Statements 

22-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

17β-Estradiol 3-O-Sulfate SodiuM Salt Usage And Synthesis

Uses

β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry.

Uses

17β-Estradiol 3-O-Sulfate Sodium Salt is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.

General Description

β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women.

Biochem/physiol Actions

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

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• 17β-Estradiol 3-O-Sulfate SodiuM Salt