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6-Fluoroquinaldine

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6-Fluoroquinaldine Basic information

Product Name:
6-Fluoroquinaldine
Synonyms:
  • 6-Fluoro-2-methylquinoline, 98+%
  • 6-Fluoro-2-methyl-1-azanaphthalene
  • AKOS 1002
  • 6-FLUORO-2-METHYLQUINOLINE
  • 6-FLUOROQUINALDINE
  • 6-Fluoro-2-methylquinoline 97%
  • 6-Fluoro-2-methylquinoline97%
  • 2-METHYL-6-FLUOROQUINOLINE
CAS:
1128-61-6
MF:
C10H8FN
MW:
161.18
EINECS:
214-439-2
Product Categories:
  • Aromatics Compounds
  • Quinolines, Quinazolines and derivatives
  • Quinoline&Isoquinoline
  • Alkylquinolines
  • Haloquinolines
  • Quinolines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Building Blocks
  • Heterocyclic Building Blocks
Mol File:
1128-61-6.mol
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6-Fluoroquinaldine Chemical Properties

Melting point:
49-53 °C (lit.)
Boiling point:
99 °C / 3mmHg
Density 
1.1465 (estimate)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in Chloroform.
pka
5.16±0.43(Predicted)
form 
powder to crystal
color 
White to Almost white
BRN 
1281677
CAS DataBase Reference
1128-61-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
38-41-36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29334990

MSDS

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6-Fluoroquinaldine Usage And Synthesis

Chemical Properties

brown powder or granules

Uses

Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Br?nsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.

Uses

Quinoline derivative as a highly potent thrombin receptor antagonist

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