2-(TRIPHENYLPHOSPHORANYLIDENE)PROPIONALDEHYDE Chemical Properties

Melting point:

219-221 °C (lit.)

Boiling point:

478.5±28.0 °C(Predicted)

Density 

1.14±0.1 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

form 

Low Melting Solid

color 

White to pink to brown

CAS DataBase Reference

24720-64-7

Safety Information

Risk Statements 

22-36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich

2-(TRIPHENYLPHOSPHORANYLIDENE)PROPIONALDEHYDE Usage And Synthesis

Chemical Properties

White to light beige crystalline powder

Uses

Reactant for:• ;Preparation of acitretin analogs with antitumor activity1• ;Stereoselective synthesis of essential building blocks of phorboxazole A via hetero Diels-Alder and stereoselective hetero-Michael addition/equilibration2• ;Preparation of C1-C14 fragment of sarcoglaucol-16-one via Z-selective ando-type Horner-Wadsworth-Emmons olefination3• ;Wittig reactions4• ;Synthesis of ring-expanded and epothilone-hybridized macrosphelide analogs as apoptosis-inducing agents5• ;Preparation of phosphonic acid-containing analogs of mycophenolic acid as inhibitors

Uses

2-(Triphenylphosphoranylidene)propionaldehyde is a reagent used in the asymmetric synthesis of hispidanin A via oxidative alkoxylation and stereoselective Diels-Alder reaction. Also acts as a reagent in the stereoselective synthesis of 10-epi-tirandamycin E.

Uses

Reactant for:

• Preparation of acitretin analogs with antitumor activity
• Stereoselective synthesis of essential building blocks of phorboxazole A via hetero Diels-Alder and stereoselective hetero-Michael addition/equilibration
• Preparation of C1-C14 fragment of sarcoglaucol-16-one via Z-selective ando-type Horner-Wadsworth-Emmons olefination
• Wittig reactions
• Synthesis of ring-expanded and epothilone-hybridized macrosphelide analogs as apoptosis-inducing agents
• Preparation of phosphonic acid-containing analogs of mycophenolic acid as inhibitors of IMPDH

2-(TRIPHENYLPHOSPHORANYLIDENE)PROPIONALDEHYDE(24720-64-7)Related Product Information

• Ethyl 2-(triphenylphosphoranylidene)propionate
• 2-(TRIPHENYLPHOSPHORANYLIDENE)SUCCINIC ANHYDRIDE
• 2-(TRIPHENYLPHOSPHORANYLIDENE)PROPIONALDEHYDE
• 2-(TRIPHENYLPHOSPHORANYLIDENE)BUTYRALDEHYDE
• 1-METHOXYCARBONYLETHYLIDENETRIPHENYLPHOSPHORANE
• ETHYL 4,4,4-TRIFLUORO-2-(TRIPHENYLPHOSPHORANYLIDENE)ACETOACETATE
• METHYL 2-[5-(4-CHLOROPHENYL)-2-HYDROXY-3-OXO-2,3-DIHYDROFURAN-2-YL]-2-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)ACETATE
• 2-[2-(4-CHLOROPHENYL)-2-OXO-1-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)ETHYL]-2-HYDROXY-5-PHENYL-2,3-DIHYDROFURAN-3-ONE
• ETHYL 2,4-DIOXO-3-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)PENTANOATE
• SPECS AE-848/33625045
• METHYL 2-(2-HYDROXY-3-OXO-5-PHENYL-2,3-DIHYDROFURAN-2-YL)-2-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)ACETATE
• METHYL 3-OXO-3-[3-(TRIFLUOROMETHYL)PHENYL]-2-(TRIPHENYLPHOSPHORANYLIDENE)PROPANOATE
• AURORA KA-1174
• AURORA KA-1073
• SALOR-INT L150010-1EA
• SALOR-INT L151815-1EA
• 4-[(4-BROMOPHENYL)(DIPHENYL)PHOSPHORANYLIDENE]-5-METHYL-2-PHENYL-2,4-DIHYDRO-3H-PYRAZOL-3-ONE
• AURORA KA-1180