CCK (26-30) (sulfated) Chemical Properties

Density 

1.459±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Water: 1 mg/ml

form 

A lyophilized powder

pka

-4.17±0.18(Predicted)

CCK (26-30) (sulfated) Usage And Synthesis

Description

CCK (26-30) is an N-terminal fragment of CCK (Item Nos. 23371 | 24404), a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-30) inhibits binding of [¹²⁵I]CCK-33 to guinea pig cortical membranes by 10% when used at a concentration of 0.1 mM.

Uses

N-acetyl CCK-(26-30) amide (CCK-(26-30) (sulfated)) is a cholecystokinin (CCK) receptor antagonist[1].

References

[1] Gardner JD, et al. N-terminal fragments of CCK-(26-33) as cholecystokinin receptor antagonists in guinea pig pancreatic acini. Am J Physiol. 1985 Jan;248(1 Pt 1):G98-102. DOI:10.1152/ajpgi.1985.248.1.G98