2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine
2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine Basic information
- Product Name:
- 2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine
- Synonyms:
-
- 2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine
- 2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-5-fluorouridine
- 2’,3’,5’-Tri-O-benzoyl-2’-C-methyl-5-fluorouridine
- 2’,3’,5’-Tri-O-benzoyl-2’-C-methyl-5-fluorouriddine
- (2R,3R,4R,5R)-3,4-dibenzoyloxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-4-methyloxolan-2-yl]methylbenzoate
- CAS:
- 2072145-49-2
- MF:
- C31H25FN2O9
- MW:
- 588.54
- Mol File:
- 2072145-49-2.mol
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2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine Chemical Properties
- Density
- 1.45±0.1 g/cm3(Predicted)
- pka
- 7.63±0.10(Predicted)
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2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine Usage And Synthesis
Uses
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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