8-Bromo-3'-deoxyguanosine
8-Bromo-3'-deoxyguanosine Basic information
- Product Name:
- 8-Bromo-3'-deoxyguanosine
- Synonyms:
-
- 8-Bromo-3'-deoxyguanosine
- Guanosine, 8-?bromo-?3'-?deoxy- (9CI)
- 8-Bromo-3’-deoxyguanosine
- 2-amino-8-bromo-9-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
- CAS:
- 847649-68-7
- MF:
- C10H12BrN5O4
- MW:
- 346.14
- Mol File:
- 847649-68-7.mol
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8-Bromo-3'-deoxyguanosine Chemical Properties
- Boiling point:
- 727.0±70.0 °C(Predicted)
- Density
- 2.45±0.1 g/cm3(Predicted)
- pka
- 13.53±0.60(Predicted)
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8-Bromo-3'-deoxyguanosine Usage And Synthesis
Uses
8-Bromo-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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